Once the rough has been approved, it's time to make a comprehensive. You may be getting tired of drawing the same thing over and over again, but this is the last one. Since it is the final drawing, take your time with it. This image will be the one used on the notepad, so make it as clean and smooth as you can. You actually have two options for this step. You can choose to draw the image and darken the lines with a tech pen or you can opt to vector it. The choice is yours. Vectoring will make lines more consistent in weight and usually more smooth, but really complex images are tough to vector so they may be better to draw. If you elect to draw your image it will need to be scanned and cleaned up in Photoshop too. The example here will show you how different the two will look, even with a not of time spent touching up the drawn one.
Once you've made your graphic(s) open up the Illustrator file that you used for the rough. The video below will walk you through the process from there.